One dataset, many instruments.
Every tool accepts a deposited signature ID, a user-uploaded gene list, or a query built from the browse facets — no export/import loop required.
Functional Enrichment
Map your signature to GO, Reactome, and KEGG pathways with FDR-controlled overrepresentation.
Similar signatures
From a signature or an uploaded gene list, find the closest signatures by directional overlap (concordant vs opposite), across species if wanted.
Compare signatures
Pick a set of 2–25 signatures and see their pairwise directional connectivity as a similarity heatmap.
Cross-species
Pick a compound tested in more than one species and see which genes respond the same way, oppositely, or in only one species.
AOP network
Explore the Adverse Outcome Pathways represented across the repository, linked where they share mechanistic Key Events.
ChemPSy · Spatial
Project chemicals into a 2D chemical-similarity space derived from signature-level transcriptional responses.
ChemPSy · Prediction
Predict likely Adverse Outcome Pathways for a query signature or gene list by read-across from its nearest neighbours in signature space.