A curated, peer-deposited repository of over- and under-expressed gene sets following exposure to environmental factors — searchable, comparable, and built for reproducible science.
Each chip reflects live catalog counts. Selections combine with AND semantics; open Advanced Search for complex boolean queries.
Every tool accepts a deposited signature ID, a user-uploaded gene list, or a query built from the browse facets — no export/import loop required.
Map your signature to GO, Reactome, and KEGG pathways with FDR-controlled overrepresentation.
From a signature or an uploaded gene list, find the closest signatures by directional overlap — concordant vs opposite — across species if wanted.
Pick a compound tested in more than one species and see which genes respond the same way, oppositely, or in only one species.
Project chemicals into a 2D chemical-similarity space derived from signature-level transcriptional responses.
Predict likely Adverse Outcome Pathways for a query signature or gene list by read-across from its nearest neighbours in signature space.
Every signature links to its parent assay, factor, and project — with per-gene fold-change tables, raw contrasts, and submitter metadata.
| Signature | Chemical | Species · Tissue | Omics | Genes (↑/↓) | Added |
|---|---|---|---|---|---|
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